Inference About Complex Relationships Using Peak Height Data from DNA Mixtures

Abstract In both criminal cases and civil cases, there is an increasing demand for the analysis of DNA mixtures involving relationships. The goal might be, example, to identify contributors a mixture where donors may be related, or infer relationship between individuals based on mixture. This paper introduces approach modelling computation with arbitrarily complex It builds extension Jacquard's condensed coefficients identity, specify compute joint relationships, not only pairwise ones, including possibility inbreeding. methodology developed applied two casework examples missing person, simulation studies performance, in which ability recover information from synthetic data known ‘true’ family structure examined. methods used analyse are implemented new KinMix R package that extends DNAmixtures allow related contributors.